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7q缺失的成熟B细胞淋巴瘤中常见缺失片段的分子描绘

Molecular delineation of the commonly deleted segment in mature B-cell lymphoid neoplasias with deletion of 7q.

作者信息

Hernández J M, Schoenmakers E F, Dal Cin P, Michaux L, Van de Ven W J, Van den Berghe H

机构信息

Center for Human Genetics, University of Leuven, Belgium.

出版信息

Genes Chromosomes Cancer. 1997 Feb;18(2):147-50.

PMID:9115965
Abstract

FISH, using 16 probes, informative for more than 30 different loci, allowed us better to delineate the common deleted region in mature B-cell lymphoid malignancies with deletions of chromosome 7. The region spans about 5 cM and is located between bands 7q31 and 7q32, between loci D7S685 and D7S514.

摘要

荧光原位杂交（FISH）使用16种探针，可用于30多个不同基因座的分析，这使我们能够更好地描绘出7号染色体缺失的成熟B细胞淋巴样恶性肿瘤中的常见缺失区域。该区域跨度约5厘摩，位于7q31和7q32带之间，基因座D7S685和D7S514之间。

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