普鲁卡因胺的不良反应。
Adverse reactions to procainamide.
作者信息
Lawson D H, Jick H
出版信息
Br J Clin Pharmacol. 1977 Oct;4(5):507-11. doi: 10.1111/j.1365-2125.1977.tb00777.x.
Abstract
1 Data from a comprehensive drug surveillance programme are analysed to provide details of procainamide use and toxicity in medical wards of teaching hospitals in five countries. 2 Out of a total of 488 recipients 9.2% had one or more adverse effect attributed to the drug; common effects being arrhythmias, gastro-intestinal upsets and drug fever. Although occasionally of major severity, no patient died as a consequence of procainamide toxicity. 3 Toxicity was directly related to total daily dose and duration of hospitalization but was not related to age, weight of the patient or presenting urea or albumin concentrations.
摘要
- 对一项全面药物监测计划的数据进行分析，以提供五个国家教学医院内科病房中普鲁卡因胺的使用情况及毒性详情。2. 在总共488名接受者中，9.2%出现了一种或多种归因于该药物的不良反应；常见的反应有心律失常、胃肠道不适和药物热。尽管偶尔会出现严重不良反应，但没有患者因普鲁卡因胺毒性而死亡。3. 毒性与每日总剂量和住院时间直接相关，但与患者的年龄、体重或就诊时的尿素或白蛋白浓度无关。
相似文献
1
Adverse reactions to procainamide.普鲁卡因胺的不良反应。
Br J Clin Pharmacol. 1977 Oct;4(5):507-11. doi: 10.1111/j.1365-2125.1977.tb00777.x.
2
Lidocaine and procainamide toxicity during treatment of ventricular arrhythmias.室性心律失常治疗期间的利多卡因和普鲁卡因胺毒性
Am J Nurs. 1976 Sep;76(9):1429-31.
3
Agranulocytosis associated with procainamide therapy--report of a case.与普鲁卡因胺治疗相关的粒细胞缺乏症——一例报告。
Am J Hosp Pharm. 1977 Dec;34(12):1362-5.
4
Adverse reactions and efficacy of high-dose procainamide therapy in resistant tachyarrhythmias.大剂量普鲁卡因胺治疗难治性快速性心律失常的不良反应及疗效
Am Heart J. 1981 Oct;102(4):797-8. doi: 10.1016/0002-8703(81)90112-5.
5
Antiarrhythmic prophylaxis with procainamide in acute myocardial infarction.急性心肌梗死中使用普鲁卡因胺进行抗心律失常预防。
N Engl J Med. 1969 Dec 4;281(23):1253-60. doi: 10.1056/NEJM196912042812301.
6
Prophylactic procainamide.预防性使用普鲁卡因胺。
N Engl J Med. 1970 Mar 5;282(10):568-9. doi: 10.1056/NEJM197003052821014.
7
8
[Ventricular flutter due to the treatment with novocainamid and strophanthin].[因使用新斯的明和毒毛花苷治疗导致的心室扑动]
Klin Med (Mosk). 1979 Nov;57(11):96-8.
9
Procainamide-induced urticarial vasculitis.普鲁卡因胺诱发的荨麻疹性血管炎。
Cutis. 1988 Nov;42(5):469-72.
10
Antiaarhythmic therapy with procainamide.普鲁卡因胺抗心律失常治疗。
Cardiovasc Nurs. 1977 Sep-Oct;13(5):17-22.
引用本文的文献
1
Bolus Intravenous Procainamide in Patients with Frequent Ventricular Ectopics during Cardiac Magnetic Resonance Scanning: A Way to Ensure High Quality Imaging.心脏磁共振扫描期间频发室性早搏患者静脉注射普鲁卡因胺推注：确保高质量成像的一种方法
Diagnostics (Basel). 2021 Jan 27;11(2):178. doi: 10.3390/diagnostics11020178.
2
Computational models for the prediction of adverse cardiovascular drug reactions.用于预测不良心血管药物反应的计算模型。
J Transl Med. 2019 May 22;17(1):171. doi: 10.1186/s12967-019-1918-z.
3
Metoclopramide: A Safe Alternative to Domperidone? A Case Report on Severe Cardiac Adverse Effects in an Older Patient.胃复安：多潘立酮的安全替代品？一例老年患者严重心脏不良反应的病例报告。
Drug Saf Case Rep. 2018 Aug 7;5(1):24. doi: 10.1007/s40800-018-0090-3.
4
Adverse effects of antiarrhythmic drugs.抗心律失常药物的不良反应。
Drugs. 1981 Jan;21(1):23-45. doi: 10.2165/00003495-198121010-00002.
5
The pharmacokinetics of slow-release procainamide.缓释普鲁卡因胺的药代动力学
Eur J Clin Pharmacol. 1978 Dec 1;14(4):261-5. doi: 10.1007/BF00560459.
本文引用的文献
1
Prophylactic procaine amide in myocardial infarction.心肌梗死中的预防性普鲁卡因酰胺
Br Heart J. 1961 Jul;23(4):421-4. doi: 10.1136/hrt.23.4.421.
2
Comprehensive drug surveillance.全面的药物监测。
JAMA. 1970 Aug 31;213(9):1455-60.
3
Pharmacokinetic of procainamide in man.普鲁卡因酰胺在人体中的药代动力学。
Ann N Y Acad Sci. 1971 Jul 6;179:370-82. doi: 10.1111/j.1749-6632.1971.tb46914.x.
4
Procainamide dosage schedules, plasma concentrations, and clinical effects.普鲁卡因胺的给药方案、血浆浓度及临床效果。
JAMA. 1971 Mar 1;215(9):1454-60.
5
Antiarrhythmic prophylaxis with procainamide in acute myocardial infarction.急性心肌梗死中使用普鲁卡因胺进行抗心律失常预防。
N Engl J Med. 1969 Dec 4;281(23):1253-60. doi: 10.1056/NEJM196912042812301.
6
The use of procaine amide and lidocaine in the treatment of cardiac arrhythmias.普鲁卡因酰胺和利多卡因在心律失常治疗中的应用。
Prog Cardiovasc Dis. 1969 May;11(6):515-34. doi: 10.1016/0033-0620(69)90004-8.
7
Agranulocytosis caused by procainamide.普鲁卡因胺引起的粒细胞缺乏症。
Scott Med J. 1972 May;17(5):165-8. doi: 10.1177/003693307201700501.
8
Procainamide-induced lupus erythematosus. Clinical and laboratory observations.普鲁卡因胺诱发的红斑狼疮。临床及实验室观察
Am J Med. 1972 Mar;52(3):338-48. doi: 10.1016/0002-9343(72)90021-6.
9
Use of plasma levels in evaluation of procainamide dosage.血浆水平在普鲁卡因酰胺剂量评估中的应用。
Br Heart J. 1974 Mar;36(3):265-70. doi: 10.1136/hrt.36.3.265.
10
Long-term use of procaine amide following acute myocardial infarction.急性心肌梗死后长期使用普鲁卡因胺。
Circulation. 1973 Jun;47(6):1204-10. doi: 10.1161/01.cir.47.6.1204.
Zotero 插件