A regenerative approach to the treatment of severe osseous defects: report of an early onset periodontitis case.

The biological principles of guided tissue regeneration (GTR) and graft materials have become widely used as methods for the treatment of severe osseous defects. An early-onset periodontitis case which includes a 3-year follow-up is presented in this case report, which demonstrates the successful use of an expanded polytetrafluoroethylene barrier membrane (ePTFE; Goretex Periodontal Material) in conjunction with natural coral bone graft (Biocoral 450). The results after 3 years illustrate the potential for regenerative periodontal therapy in combination with appropriate prosthetic procedures where limited success might have been expected.