Tsumoto T, Yasuda H, Fukuda M, Akaneya Y
Department of Neurophysiology, Osaka University Medical School, Suita City, Japan.
J Physiol Paris. 1996;90(3-4):151-6. doi: 10.1016/s0928-4257(97)81414-3.
In this paper we describe some of the results obtained from recent experiments on mechanisms underlying long-term potentiation (LTP) and long-term depression (LTD) in the visual cortex of young rats. In particular, we focus on experiments which tested the hypotheses that the induction of LTP in the visual cortex is of Hebbian type and that an input-associated Ca2+ rise at postsynaptic sites and subsequent activation of protein kinases or protein phosphatases may play roles in the induction of LTP or LTD in the developing visual cortex.
在本文中，我们描述了一些近期针对幼鼠视觉皮层中长时程增强（LTP）和长时程抑制（LTD）潜在机制的实验所获得的结果。特别地，我们着重于那些检验以下假设的实验：视觉皮层中LTP的诱导属于赫布型，并且突触后位点与输入相关的Ca2+升高以及随后蛋白激酶或蛋白磷酸酶的激活可能在发育中的视觉皮层LTP或LTD的诱导中发挥作用。
