Sare M, Yesilada O, Gürel M, Balkaya M, Yologlu S, Fiskin K
Department of General Surgery, Faculty of Medicine, Inönü University, Malatya, Turkey.
Surg Laparosc Endosc. 1997 Feb;7(1):38-41.
The effects of i.p. CO2 insufflation on bacterial proliferation in a setting of Escherichia coli-induced experimental peritonitis was studied in a rat model. Six male Wistar rats were given 0.25 ml of i.p. saline and formed the sham operation group. Twenty-four rats were divided into three groups, and all had i.p. E. coli injections. Microorganism counts were taken after 8 h in all groups. Group 1 was used as the control group. Group 2 (laparoscopy) was insufflated with CO2, and group 3 (laparotomy) had a midline laparotomy. Microorganism counts were repeated 8 h after the procedures (16 h after i.p. E. coli inoculation). Postoperative microorganism counts were significantly higher in the CO2 insufflation group (p < 0.05) compared with the control and laparotomy groups and showed an increase, whereas they decreased in the other two groups.
在大鼠模型中研究了腹腔内二氧化碳气腹对大肠杆菌诱导的实验性腹膜炎环境中细菌增殖的影响。六只雄性Wistar大鼠腹腔注射0.25 ml生理盐水，组成假手术组。二十四只大鼠分为三组，均腹腔注射大肠杆菌。所有组在8小时后进行微生物计数。第1组作为对照组。第2组（腹腔镜检查）进行二氧化碳气腹，第3组（剖腹手术）进行中线剖腹手术。在手术后8小时（腹腔注射大肠杆菌接种后16小时）重复进行微生物计数。与对照组和剖腹手术组相比，二氧化碳气腹组术后微生物计数显著更高（p < 0.05），且呈增加趋势，而其他两组则下降。
