Anderson G M, Pinfold S P, Hux J E, Naylor C D
Institute for Clinical Evaluative Sciences, North York, Ontario.
Can J Cardiol. 1997 Mar;13(3):246-52.
To compare the types of patients selected for coronary angiography (CA) and coronary artery bypass graft (CABG) surgery, and the appropriateness of the procedures performed on these patients in a random sample of cases in British Columbia and Ontario.
Retrospective randomized medical record review.
All hospitals performing CA and/or CABG in British Columbia and Ontario in fiscal year 1989/90.
For CA, 395 randomly selected patients in Ontario and 139 randomly selected patients in British Columbia; for CABG, 431 randomly selected patients in Ontario and 125 randomly selected patients in British Columbia.
Case selection was measured in terms of the demographic and clinical characteristics of patients undergoing the procedures. Appropriateness was measured by comparing the clinical characteristics of patients undergoing the procedures with explicit criteria established by a panel of Canadian physicians. The yield from CA was measured as the proportion of patients who were found to have insignificant anatomical disease.
Analysis of patients selected for CA showed that sample patients from Ontario were less likely than those from British Columbia to be female (25% versus 37%, respectively, P = 0.012) and less likely to have undergone a previous revascularization (12% versus 24%, respectively, P = 0.005). The distribution of main indications for CA differed between the two provinces (P = 0.002), with Ontario patients more likely to have chronic stable angina (45% versus 24%) and less likely to have unstable angina (16% versus 26%). For CABG, sample patients from Ontario were less likely to be 65 years of age or older (32% versus 45%, P = 0.016) and more likely to have an ejection fraction less than 35% (14% versus 5%, P = 0.006). The distribution of the main indications for CABG differed (P < 0.001), with Ontario patients more likely to have chronic stable angina (68% versus 38%) and less likely to have unstable angina (20% versus 43%). There was no statistically significant difference in CA cases rated as inappropriate (8.4% in Ontario versus 10.8% in British Columbia, P = 0.396) or CABG cases rated as inappropriate (3.9% in Ontario versus 2.4% in British Columbia, P = 0.393). There were no statistically significant differences in the proportion of CA that yielded insignificant anatomical disease (17.5% in Ontario versus 18.4% in British Columbia, P = 0.355).
There were differences between Ontario and British Columbia in the demographic and clinical characteristics of patients selected for CA and CABG. This may indicate differences in the referral process in the two provinces. Despite these differences the rates of inappropriate procedures and the yield from CA were similar.
在不列颠哥伦比亚省和安大略省的随机病例样本中,比较接受冠状动脉造影(CA)和冠状动脉旁路移植术(CABG)的患者类型,以及对这些患者所实施手术的合理性。
回顾性随机病历审查。
1989/90财政年度在不列颠哥伦比亚省和安大略省所有实施CA和/或CABG的医院。
对于CA,安大略省随机选取395例患者,不列颠哥伦比亚省随机选取139例患者;对于CABG,安大略省随机选取431例患者,不列颠哥伦比亚省随机选取125例患者。
根据接受手术患者的人口统计学和临床特征来衡量病例选择情况。通过将接受手术患者的临床特征与一组加拿大医生制定的明确标准进行比较来衡量合理性。CA的检出率以发现解剖学病变不显著的患者比例来衡量。
对接受CA的患者分析显示,安大略省的样本患者比不列颠哥伦比亚省的样本患者女性比例更低(分别为25%对37%,P = 0.012),且既往接受血运重建的可能性更小(分别为12%对24%,P = 0.005)。两个省份CA的主要适应证分布不同(P = 0.002),安大略省患者患慢性稳定型心绞痛的可能性更大(45%对24%),患不稳定型心绞痛的可能性更小(16%对26%)。对于CABG,安大略省的样本患者65岁及以上的可能性更小(32%对45%,P = 0.016),射血分数低于35%的可能性更大(14%对5%,P = 0.006)。CABG的主要适应证分布不同(P < 0.001),安大略省患者患慢性稳定型心绞痛的可能性更大(68%对38%),患不稳定型心绞痛的可能性更小(20%对43%)。评定为不适当的CA病例(安大略省为8.4%,不列颠哥伦比亚省为10.8%,P = 0.396)或评定为不适当的CABG病例(安大略省为3.9%,不列颠哥伦比亚省为2.4%,P = 0.393)之间无统计学显著差异。CA检出解剖学病变不显著的比例(安大略省为17.5%,不列颠哥伦比亚省为18.4%,P = 0.355)也无统计学显著差异。
安大略省和不列颠哥伦比亚省在接受CA和CABG的患者人口统计学和临床特征方面存在差异。这可能表明两省在转诊过程中存在差异。尽管存在这些差异,但不适当手术的发生率和CA的检出率相似。