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Folate intake in young women and their knowledge of preconceptional folate supplementation to prevent neural tube defects.

作者信息

Wild J, Schorah C J, Maude K, Levene M I

机构信息

Centre for Reproduction, Growth and Development, School of Medicine, University of Leeds, UK.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1996 Dec 27;70(2):185-9. doi: 10.1016/s0301-2115(95)02584-7.

DOI:10.1016/s0301-2115(95)02584-7
PMID:9119101
Abstract

OBJECTIVES

To ascertain knowledge of periconceptional folate for prevention of neural tube defect (NTD) and to estimate folate intake in young women.

STUDY DESIGN

Three hundred young women were questioned about their knowledge of folate for prevention of NTD. Their folate intake was assessed by food frequency questionnaire.

RESULTS

Fourteen per cent of 16-19 year olds and 41% of undergraduates were aware of the need to increase folate intake before conception. Median folate intake was estimated to be 235 micrograms/d in 16-19 year olds and 248.5 micrograms/d in undergraduates. More than a quarter of women in both groups had folate intakes less than the reference nutrient intake (RNI) (200 micrograms/d) below which prevalence of NTD rises dramatically and these women would therefore be at increased risk of having a child with NTD should they have an unplanned pregnancy.

CONCLUSIONS

Strategies are required to increase folate intake among young women and inform them of the benefit of peri-conceptional folate supplementation.

摘要

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