Watari H, Yamada H, Fujino T, Okuyama K, Sagawa T, Makinoda S, Fujimoto S
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan.
Eur J Obstet Gynecol Reprod Biol. 1996 Dec 27;70(2):201-3. doi: 10.1016/s0301-2115(95)02547-2.
We report the first case of an intrauterine treatment for cystic hygroma. Guided by ultrasonography, we first removed intracystic fluid from two cysts and then injected OK-432 into each fetal cyst at 21 and 28 weeks of gestation. No re-enlargement of the cysts was subsequently observed. At 38 weeks of gestation, a male infant was delivered transvaginally. Only a slight skin fold was observed in the nuchal area of the neonate, indicating the effectiveness of OK-432 for the intrauterine treatment of cystic hygroma.
我们报告了第一例宫内治疗囊状水瘤的病例。在超声引导下，我们首先从两个囊肿中抽出囊内液体，然后在妊娠21周和28周时向每个胎儿囊肿内注射OK-432。随后未观察到囊肿再次增大。妊娠38周时，经阴道分娩出一名男婴。在新生儿的颈部区域仅观察到轻微的皮肤褶皱，表明OK-432对宫内治疗囊状水瘤有效。
