Evsiukov A N, Zhukova O V, Sheremet'eva V A, Shneĭder Iu V, Rychkov Iu G
Genetika. 1996 Nov;32(11):1583-91.
A significant geographical correlation (r = 0.719) was found between the logarithm of effective size (InNe) and heterozygosity level (H) in populations under the assumption of the Hardy-Weinberg equilibrium. The area of highest positive correlation was positioned meridionally between the Ob and Yenisei rivers, from the Arctic coast of Taimyr Peninsula to eastern Sayans and the southern Cis-Baikal region, i.e., in the same region where the highest distribution density of mean Ne values was found. Two additional areas of high correlations were found on the northern Black Sea coast and in the lower Lena river region. Analysis and mapping of correlation ratios eta H/lnNe2 and eta lnNe/H2 revealed that effective size substantially influenced heterozygosity level (as could be expected in the case of an intense gene drift), and heterozygosity level influenced effective size to the same extent. The latter relationship indicated an intense adaptation, and changes in diversity of the gene pool caused substantial demographic changes. However, this might be accounted for by direct gene migration into a population prevailing over reverse migration, i.e., mechanical population growth prevailing over natural growth.
在哈迪-温伯格平衡假设下，发现有效种群大小的对数（InNe）与种群杂合度水平（H）之间存在显著的地理相关性（r = 0.719）。正相关性最高的区域位于鄂毕河和叶尼塞河之间的经线上，从泰梅尔半岛的北极海岸到东萨彦岭和贝加尔湖西部地区，即在平均Ne值分布密度最高的同一区域。在黑海北部海岸和勒拿河下游地区还发现了另外两个高相关区域。对相关比率eta H/lnNe2和eta lnNe/H2的分析和绘图表明，有效种群大小对杂合度水平有实质性影响（在强烈基因漂变的情况下可以预期），杂合度水平对有效种群大小的影响程度相同。后一种关系表明存在强烈的适应性，基因库多样性的变化导致了大量的人口结构变化。然而，这可能是由于直接基因迁入种群的情况超过了反向迁移，即机械性种群增长超过了自然增长。
