Viedma A, Jiménez-Ortiz C, Marco V
Escuela Politécnica Superior, Univ. de Murcia, Cartagena, Spain.
J Biomech. 1997 Mar;30(3):265-72. doi: 10.1016/s0021-9290(96)00143-1.
A fluid-dynamic model of the circle of Willis and its periorbital links with the external carotid arteries has been established and tested. It is based on anatomic data and takes Doppler measurements as flow input conditions. The model explains, on fluid-dynamic grounds, the clinical observations of periorbital reverse flow and arrival pulse time delay. It also obtains the velocity and pressure pulse at any point of the studied area. This allows the comparison between the normal or healthy condition and the flow distribution when an internal carotid is externally or pathologically occluded. Several combinations of the communicating artery sizes are explored to obtain the reduced cerebral flow. The combination of the communicating diameters can lead to insufficient irrigation which can be hydrodynamically assessed. No other physiological response is included, and the results must be considered as a minimum assured. These results show the need for a common evaluation of the alternative paths and explain some paradoxes found in literature.
已建立并测试了 Willis 环及其与颈外动脉眶周连接的流体动力学模型。该模型基于解剖学数据，并将多普勒测量结果作为血流输入条件。该模型从流体动力学角度解释了眶周逆流和到达脉冲时间延迟的临床观察结果。它还能获取研究区域内任意点的速度和压力脉冲。这使得能够比较正常或健康状态与颈内动脉外部或病理性闭塞时的血流分布。探索了几种交通动脉大小的组合以获得减少的脑血流量。交通动脉直径的组合可能导致灌注不足，这可以通过流体动力学进行评估。未纳入其他生理反应，结果必须被视为最低限度的保证。这些结果表明需要对替代路径进行共同评估，并解释了文献中发现的一些矛盾之处。
