Bulochnik E D, Kurbatov M G
Biull Eksp Biol Med. 1977 Oct;84(10):408-11.
Experiments were conducted on cats, anesthetized with nembutal. The influence of local heating of the sensomotor cortex on the transcallosum response was examined. It was revealed that heating for short and long periods of limited regions of the cortex of both hemispheres induced a primary depression of the negative component of the transcallosum response at 44 degrees C and above it. The depression was replaced by an irreversible block of both response phases at 47--49 degrees C. It was concluded that the direct inhibitory influence of high temperatures on the cortical neurons was expressed only within the range of extreme temperature incompatible with vital activity of the whole organism. Experiments with the thermal block of the hemisphere region could testify to the fact that the transcallosum responses occurred mainly as a result of the direct irritation of the callosum fibers by stimulating electrodes and entirely reflected the post-synaptic potentials.
实验在使用戊巴比妥麻醉的猫身上进行。研究了感觉运动皮层局部加热对胼胝体反应的影响。结果显示,对两个半球皮层的有限区域进行短期和长期加热,在44摄氏度及以上时会导致胼胝体反应负成分的原发性抑制。在47 - 49摄氏度时,这种抑制被反应两个阶段的不可逆阻断所取代。得出的结论是,高温对皮层神经元的直接抑制作用仅在与整个生物体生命活动不相容的极端温度范围内表现出来。对半球区域进行热阻断的实验可以证明,胼胝体反应主要是由于刺激电极直接刺激胼胝体纤维而产生的,并且完全反映了突触后电位。