Rehman J, Benet A, Minsky L S, Melman A
Department of Urology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA.
J Urol. 1997 Apr;157(4):1288-91. doi: 10.1016/s0022-5347(01)64953-x.
We report a modification of the Nesbit plication with partial thickness shaving instead of conventional excision of a wedge of tunica albuginea. The technique minimizes intraoperative bleeding, obviates cavernous tissue damage and improves adhesion of plicated tunical layers.
Between September 1988 and September 1994, 32 patients underwent modified plication repair of chordee secondary to Peyronie's disease (26) or congenital penile deviation (6). The results were evaluated in the spring of 1996.
Mean age plus or minus standard deviation was 55 +/- 8.8 years for patients with Peyronie's disease and 27 +/- 6.85 years for those with congenital penile deviation. Mean duration of Peyronie's disease was 22 +/- 9 months. Eight patients complained of erectile dysfunction and penile curvature. Plication for congenital deviation (6 patients) resulted in 100% satisfaction with the surgical result. Of the 26 men with Peyronie's disease 19 (78%) reported a good to excellent outcome. With prolonged followup (1 to 5 years) 7 patients had recurrent curvature due to progression of disease, including 5 with mild curvature who were able to have intercourse, in contrast with 2 who had severe early recurrence of deformity (more than 30 degrees) within 1 year postoperatively and underwent a second modified plication with good clinical outcome. Six of 32 patients with peyronie's disease were unable to resume satisfactory coitus with a postoperative straight penis. All 6 patients had concomitant poor erections preoperatively as shown by nocturnal peniletumescence and rigidity testing and 5 of them resumed regular intercourse with intracavernous pharmacotherapy.
Long-term results of this modified plication demonstrate excellent clinical outcome with minimal morbidity.
我们报告了对Nesbit折叠术的一种改良,采用部分厚度削薄而非传统的白膜楔形切除。该技术可减少术中出血,避免海绵体组织损伤,并改善折叠的白膜层的粘连。
1988年9月至1994年9月期间,32例患者接受了改良折叠修复术,用于治疗佩罗尼氏病继发的阴茎弯曲(26例)或先天性阴茎弯曲(6例)。1996年春季对结果进行了评估。
佩罗尼氏病患者的平均年龄±标准差为55±8.8岁,先天性阴茎弯曲患者为27±6.85岁。佩罗尼氏病的平均病程为22±9个月。8例患者抱怨勃起功能障碍和阴茎弯曲。先天性弯曲的折叠术(6例患者)使患者对手术结果的满意度达到100%。26例佩罗尼氏病男性患者中,19例(78%)报告结果良好至优秀。经过长期随访(1至5年),7例患者因疾病进展出现复发性弯曲,其中5例轻度弯曲患者能够进行性交,相比之下,2例患者术后1年内出现严重早期畸形复发(超过30度),并接受了第二次改良折叠术,临床效果良好。32例佩罗尼氏病患者中有6例术后阴茎伸直后仍无法恢复满意的性交。所有6例患者术前夜间阴茎勃起和硬度测试均显示勃起功能差,其中5例通过海绵体内药物治疗恢复了规律性交。
这种改良折叠术的长期结果显示出极佳的临床效果,且发病率极低。