Gusman B S, Vasil'eva V I, Bezuglova T V, Asratian A A
Biull Eksp Biol Med. 1977 Sep;84(9):372-5.
Respiratory organs of newborn rats inoculated intranasally with broth culture of Myc. hominis were studied by the histological, histochemical and immunofluorescence methods. Tracheitis and development of purulent and interstitial pneumonia with a hemorrhagic component were revealed 24 hours after the infection. These changes were observed up to the 7th day of the experiment. At the same period a specific fluorescence of the Myc. hominis antigen was found by the antibody fluorescent test. The present study pointed to the pathogenicity of the Myc. hominis for the respiratory tract of the newborn rats.
采用组织学、组织化学和免疫荧光方法，对经鼻接种人型支原体肉汤培养物的新生大鼠的呼吸器官进行了研究。感染后24小时，可见气管炎症以及伴有出血成分的化脓性和间质性肺炎的发展。这些变化在实验的第7天一直存在。同一时期，通过抗体荧光试验发现了人型支原体抗原的特异性荧光。本研究表明人型支原体对新生大鼠的呼吸道具有致病性。
