Neuhaus T J, Schwöbel M, Schlumpf R, Offner G, Leumann E, Willi U
University Children's Hospital, Zürich, Switzerland.
J Urol. 1997 Apr;157(4):1400-3.
We assessed morbidity and risk factors of pyelonephritis in children after renal transplantation.
Between 1986 and 1995, 41 children underwent transplantation and all who had documented pyelonephritis were evaluated.
Six children who underwent transplantation before age 7 years had 1 to 3 episodes of pyelonephritis with significant renal dysfunction and vesicoureteral reflux into the grafted system. An antireflux reimplantation procedure in 5 children was complicated by temporary functional obstruction in 3. No further infection occurred after correction of vesicoureteral reflux. After a median of 4.5 years post-transplantation all patients have a functioning graft.
After renal transplantation vesicoureteral reflux and young recipient age are major risk factors for pyelonephritis with subsequent graft dysfunction.
我们评估了肾移植术后儿童肾盂肾炎的发病率及危险因素。
1986年至1995年间，41例儿童接受了移植手术，并对所有有记录的肾盂肾炎患儿进行了评估。
6例7岁前接受移植的儿童发生了1至3次肾盂肾炎，伴有明显的肾功能障碍以及膀胱输尿管反流至移植肾系统。5例儿童接受抗反流再植手术，其中3例出现暂时性功能梗阻并发症。纠正膀胱输尿管反流后未再发生感染。移植术后中位时间4.5年后，所有患者的移植肾均功能良好。
肾移植术后，膀胱输尿管反流和受者年龄小是发生肾盂肾炎并导致移植肾功能障碍的主要危险因素。
