Christensen M H, Schulze S, Rosenberg J
Organkirurgisk afdeling, H:S Sundby Hospital.
Ugeskr Laeger. 1997 Mar 24;159(13):1954-5.
Nitroglycerine, acting a nitric oxide donor, is known to relax visceral smooth muscle. We report a case where pain associated with pancreatitis after ERCP was successfully treated with sublingual nitroglycerine 0.5 mg. The analgesic effect lasted approximately two hours. Further controlled studies should evaluate the effect of nitroglycerine on pain associated with pancreatitis as well as clarify the mechanisms involved.
硝酸甘油作为一种一氧化氮供体,已知可松弛内脏平滑肌。我们报告了一例在内镜逆行胰胆管造影术后与胰腺炎相关的疼痛,通过舌下含服0.5毫克硝酸甘油成功得到治疗的病例。镇痛效果持续了约两小时。进一步的对照研究应评估硝酸甘油对与胰腺炎相关疼痛的影响,并阐明其中涉及的机制。