Davie I T, Slawson K B
Br J Anaesth. 1976 Sep;48(9):915-8. doi: 10.1093/bja/48.9.915.
The preoperative effects of oral oxypertine have been compared with those of papaveretum and atropine in 185 patients in a double-blind between-patient study. Oxypertine 20 mg given orally as a nocturnal sedative and again on the morning of operation produced relief of anxiety comparable to that of papaveretum 10 mg and atropine 0.6 mg. It is concluded that oxypertine may be of value in medication before anaesthesia.
在一项针对185例患者的双盲患者间研究中,对口服奥昔哌汀的术前效果与罂粟碱和阿托品的效果进行了比较。术前夜间口服20毫克奥昔哌汀,手术当天上午再服一次,其缓解焦虑的效果与10毫克罂粟碱和0.6毫克阿托品相当。得出的结论是,奥昔哌汀在麻醉前用药中可能有价值。