Piver M S, Barlow J J
Cancer. 1977 Mar;39(3):1243-6. doi: 10.1002/1097-0142(197703)39:3<1243::aid-cncr2820390333>3.0.co;2-t.
Twenty-one women with biopsy proven aortic node metastases from previously untreated carcinoma of the uterine cervix were treated with high dose irradiation to the pelvis and para-aortic areas. The majority received 6000 rads to the pelvis and para-aortic nodes by split course therapy plus 2500 rads by intracavitary radium to point A; 57.1% sustained severe complications to the stomach, small intestine or colon. Only 14.2% are surviving over 2 years free of recurrence. Though approximately 40% of women with Stages III and IV cervical cancer will have metastases to the para-aortic nodes, to date there is no satisfactory therapy that results in a significant number of such women surviving free of recurrent cervical cancer.
21名经活检证实有主动脉旁淋巴结转移的未接受过治疗的子宫颈癌患者接受了盆腔和腹主动脉旁区域的高剂量放疗。大多数患者通过分段放疗接受6000拉德的盆腔和腹主动脉旁淋巴结照射，再加上腔内镭疗给予A点2500拉德；57.1%的患者出现了胃、小肠或结肠的严重并发症。只有14.2%的患者存活超过2年且无复发。虽然约40%的III期和IV期宫颈癌女性会出现腹主动脉旁淋巴结转移，但迄今为止，尚无令人满意的治疗方法能使大量此类女性存活且无复发性宫颈癌。
