Chen C P, Shih S L, Liu F F, Jan S W, Lin Y N, Lan C C
Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan, ROC.
Pediatr Radiol. 1997 Mar;27(3):221-5. doi: 10.1007/s002470050105.
A morphology based imaging review is presented of the characteristic skeletal deformities associated with acardius anceps in three acardiac twins. These fetuses demonstrated poorly developed skulls, limb reduction defects, and phocomelia of the upper limbs, as well as narrow thoracic cages with or without the complete development of ribs, clavicles, scapulae, and cervical, thoracic, or lumbar vertebrae. However, their lower limbs and pelvic girdles were almost normal. The authors conclude that skeletal development is likely to be jeopardized in the area adjacent to the heart and in the cephalic portion of the body in fetuses with acardius anceps, and suggest vascular deficiency and hypoperfusion as pathogenetic mechanisms in this type of skeletal deformity.
本文对三例无心畸胎孪生儿中与无心畸胎相关的特征性骨骼畸形进行了基于形态学的影像学综述。这些胎儿表现出头颅发育不良、肢体短小畸形以及上肢海豹肢畸形，同时胸廓狭窄，肋骨、锁骨、肩胛骨以及颈椎、胸椎或腰椎发育不全或完全未发育。然而，他们的下肢和骨盆带几乎正常。作者得出结论，无心畸胎胎儿心脏附近区域和身体头部的骨骼发育可能受到损害，并提出血管缺乏和灌注不足是这类骨骼畸形的发病机制。
