1型神经纤维瘤病患儿中消失的强化脑病变

Disappearing enhancing brain lesion in a child with neurofibromatosis type I.

作者信息

Morris P W, Glasier C M, Smirniotopoulos J G, Allison J W

机构信息

Department of Pediatrics, Arkansas Children's Hospital, Little Rock 72202-3591, USA.

出版信息

Pediatr Radiol. 1997 Mar;27(3):260-1. doi: 10.1007/s002470050118.

DOI:10.1007/s002470050118

PMID:9126587

Abstract

Neurofibromatosis type 1 (NF1) in children can produce a variety of parenchymal signal abnormalities on cranial MR. Areas of abnormal signal in these patients may represent regions of disordered myelination, "hamartomatous" change or frank neoplasia. The presence of contrast enhancement in intracranial lesions in patients with NF1 is usually strongly suggestive of tumor. We report the case of a child with NF1 and a focal enhancing brain parenchymal lesion which spontaneously resolved without specific therapy.

摘要

儿童1型神经纤维瘤病（NF1）在头颅磁共振成像（MR）上可产生多种实质信号异常。这些患者的异常信号区域可能代表髓鞘形成紊乱、“错构瘤样”改变或明显的肿瘤形成区域。NF1患者颅内病变出现对比增强通常强烈提示肿瘤。我们报告一例患有NF1的儿童，其脑实质有局灶性强化病变，未经特殊治疗自行消退。