Morimura Y, Hoshi K, Watanabe F, Honda T, Yamada H, Sato A
Department of Obstetrics and Gynecology, Fukushima Medical College, Japan.
Tohoku J Exp Med. 1996 Dec;180(4):319-26. doi: 10.1620/tjem.180.319.
To clarify the influence of age on clinical and histologic features, young women with ovarian epithelial borderline tumors and carcinomas were analyzed. A retrospective review of 93 patients with ovarian common epithelial borderline tumors and carcinomas was performed. Twenty-one of 93 patients (22.6%) were under age 40. Predominant symptoms in young patients were abdominal pain or abdominal distention, but 4 (19%) patients had no symptom. Eleven (11/21; 52.4%) patients were nulliparous and six patients received conservative surgery to preserve fertility. The rate of histologic type and stage did not significantly differ between the young and older groups. Although overall survival between young and older patients did not significantly differ, the survival of young patients with advanced disease (stage III and IV) was significantly worse than in older patients with advanced disease. (p < 0.05).
为阐明年龄对临床和组织学特征的影响,对患有卵巢上皮交界性肿瘤和癌的年轻女性进行了分析。对93例卵巢常见上皮交界性肿瘤和癌患者进行了回顾性研究。93例患者中有21例(22.6%)年龄在40岁以下。年轻患者的主要症状为腹痛或腹胀,但有4例(19%)患者无症状。11例(11/21;52.4%)患者未生育,6例患者接受了保留生育功能的保守手术。年轻组和老年组之间的组织学类型和分期发生率无显著差异。虽然年轻患者和老年患者的总生存率无显著差异,但晚期疾病(III期和IV期)的年轻患者生存率明显低于晚期疾病的老年患者。(p<0.05)