急性低氧血症对清醒男性血浆精氨酸加压素的影响。

Effect of acute hypoxaemia on plasma arginine vasopressin in conscious man.

Baylis P H, Stockley R A, Heath D A

Clin Sci Mol Med. 1977 Oct;53(4):401-4. doi: 10.1042/cs0530401.

Abstract

Acute hypoxaemia had been reported to stimulate vasopressin release in animals. 2. Hypoxaemia induced by breathing 9-3% oxygen for 15-20 min failed to produce a rise in plasma arginine vasopressin concentration in six out of eight healthy human subjects. The two subjects who developed an increase in plasma arginine vasopressin concentration had a significant rise in serum cortisol. 3. Breathing 100% nitrogen until impairment of consciousness caused no rise in plasma arginine vasopressin concentration.

摘要

据报道，急性低氧血症会刺激动物体内抗利尿激素的释放。2. 对8名健康受试者中的6名进行15 - 20分钟9% - 3%氧气呼吸诱导低氧血症，并未使血浆精氨酸抗利尿激素浓度升高。血浆精氨酸抗利尿激素浓度升高的两名受试者血清皮质醇显著升高。3. 呼吸100%氮气直至意识障碍，血浆精氨酸抗利尿激素浓度未升高。