Hackett L P, Dusci L J
Clin Toxicol. 1977;11(3):341-52. doi: 10.3109/15563657708989849.
A rapid analytical procedure is described for a variety of drugs that could be present in the overdosed patient. The technique used gives quantitative results for most of the drugs analyzed in serum using gas chromatography and incorporates thin-layer chromatography and spot tests for drug confirmation. The procedure is novel for it relies on the initial extraction of acidics, basics, and neutrals from serum acidified with hydroxhloric acid.
本文描述了一种针对过量服药患者体内可能存在的多种药物的快速分析方法。所采用的技术通过气相色谱法对血清中分析的大多数药物给出定量结果,并结合薄层色谱法和斑点试验进行药物确证。该方法新颖之处在于它首先从用盐酸酸化的血清中提取酸性、碱性和中性药物。