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宫颈狭窄患者取卵时的宫颈扩张:对体外受精-胚胎移植程序中妊娠结局的影响

Cervical dilatation during ovum pick-up in patients with cervical stenosis: effect on pregnancy outcome in an in vitro fertilization-embryo transfer program.

作者信息

Groutz A, Lessing J B, Wolf Y, Yovel I, Azem F, Amit A

机构信息

IVF-ET Unit, Serlin Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.

出版信息

Fertil Steril. 1997 May;67(5):909-11. doi: 10.1016/s0015-0282(97)81405-7.

DOI:10.1016/s0015-0282(97)81405-7
PMID:9130898
Abstract

OBJECTIVE

To evaluate the results of cervical dilatation during an ovum pick-up session in patients with cervical stenosis who participated in an IVF-ET program.

DESIGN

A retrospective study.

SETTING

In vitro fertilization-ET unit.

PATIENT(S): Forty-one treatment cycles in 22 patients with known cervical stenosis. In all patients previous transcervical ET had been either extremely difficult or impossible.

INTERVENTION(S): Cervical dilatation under general anesthesia during an ovum pick-up session, 48 hours before transcervical ET.

MAIN OUTCOME MEASURE(S): Ease of ET procedure and clinical pregnancy rate (PR).

RESULT(S): Cervical dilatation was performed in 41 IVF-ET cycles and resulted in easier transcervical ET in 39 cycles, but only one clinical and one extrauterine pregnancy.

CONCLUSION(S): Cervical dilatation during the ovum pick-up session leads to easier ET in patients with cervical stenosis, but PRs after this procedure are very low.

摘要

目的

评估参与体外受精-胚胎移植(IVF-ET)项目的宫颈狭窄患者在取卵过程中宫颈扩张的效果。

设计

一项回顾性研究。

地点

体外受精-胚胎移植科室。

患者

22例已知宫颈狭窄患者的41个治疗周期。所有患者既往经宫颈胚胎移植均极其困难或无法进行。

干预措施

在经宫颈胚胎移植前48小时取卵过程中全身麻醉下进行宫颈扩张。

主要观察指标

胚胎移植操作的难易程度及临床妊娠率(PR)。

结果

41个IVF-ET周期进行了宫颈扩张,其中39个周期经宫颈胚胎移植更容易,但仅1例临床妊娠和1例宫外孕。

结论

取卵过程中宫颈扩张使宫颈狭窄患者的胚胎移植更容易,但该操作后的临床妊娠率非常低。

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