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[哮喘死亡与濒死性哮喘发作的比较]

[A comparison of asthma deaths and near-fatal asthma attacks].

作者信息

Sudo M, Kobayashi H, Nakagawa T, Kabe J, Tadashi H, Sano Y, Osakabe Y, Akiyama K, Miyagi S, Jyo T, Ueda N

机构信息

Morioka Yuai Hospital.

出版信息

Arerugi. 1996 Dec;45(12):1262-9.

PMID:9133337
Abstract

This study compares the characteristics of fatal asthma patients and those of near-fatal asthma patients who had experienced severe life threatening attacks. Data from 67 fatal asthma patients and 80 near-fatal asthma patients were analyzed. The mean age of fatal asthma cases were older than near-fatal asthma cases, 51.9 yrs and 44.3 yrs, respectively. Similarities of the two cases were seen in sex, type of asthma and severity of asthma. The experiences of previous life-threatening asthma did not differ in both groups (43.3% of fatal vs 40.0% of near-fatal). From the viewpoint of type of development of severe exacerbation, rapid exacerbation was more frequent in fatal cases than near-fatal cases, but acute exacerbation after unstable asthma was more in near-fatal asthma. Seventy-six percent of all asthma deaths occurred at home or on the way to the emergency department. The rate of delay of receiving medical care was significantly higher in fatal cases (72%) than near-fatal cases (26%). There was no significant difference in the frequency of medical management before fatal or near-fatal episode such as oxygen therapy, mechanical ventilation. Use of ambulance, visiting emergency department, previous hospitalization between the two groups. The profile of fatal cases was almost same to that of near-fatal cases except delay of receiving medical care. In conclusion, the analysis of near-fatal cases was very important to make clear the causes of asthma death.

摘要

本研究比较了致命性哮喘患者与经历过严重危及生命发作的濒死性哮喘患者的特征。分析了67例致命性哮喘患者和80例濒死性哮喘患者的数据。致命性哮喘病例的平均年龄大于濒死性哮喘病例,分别为51.9岁和44.3岁。两组在性别、哮喘类型和哮喘严重程度方面存在相似之处。两组既往危及生命的哮喘经历无差异(致命性哮喘组为43.3%,濒死性哮喘组为40.0%)。从严重加重发作类型的角度来看,致命性病例中快速加重比濒死性病例更常见,但不稳定哮喘后的急性加重在濒死性哮喘中更多见。所有哮喘死亡病例中有76%发生在家中或前往急诊科的途中。致命性病例接受医疗救治的延迟率(72%)显著高于濒死性病例(26%)。在致命或濒死发作前的医疗处理频率,如氧疗、机械通气方面,两组之间无显著差异。两组在使用救护车、前往急诊科、既往住院情况方面也无差异。除了接受医疗救治的延迟情况外,致命性病例的情况与濒死性病例几乎相同。总之,分析濒死性病例对于明确哮喘死亡原因非常重要。

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