[镁离子的抗心律失常作用。强心治疗期间对心室兴奋性的保护]
[Anti-arrhythmic effect of magnesium cations. Protection against ventricular excitability during cardiotonic therapy].
作者信息
Critelli G, Ferro G, Adinolfi L, Perticone F, Maione S, Condorelli M
出版信息
Arch Mal Coeur Vaiss. 1979 Aug;72(8):879-83.
This study showed the effectiveness of magnesium sulphate during digitalis therapy complicated by ventricular hyperexcitability. 28 patients with cardiac disease and ventricular arrhythmias in heart failure were studied. Magnesium sulphate was given by slow intravenous infusion (30--50 mg/min) twice daily. The anti-arrhytmic action allowed treatment with digitalis until improvement in cardiac function was observed. The mechanism of the action of magnesium sulphate in digitalis--induced arrhythmias is discussed.
本研究显示了硫酸镁在洋地黄治疗并发心室过度兴奋时的有效性。对28例患有心脏病且心力衰竭伴有室性心律失常的患者进行了研究。硫酸镁通过缓慢静脉输注（30 - 50毫克/分钟），每日两次给药。抗心律失常作用使得可以继续使用洋地黄治疗，直至观察到心功能改善。文中讨论了硫酸镁在洋地黄所致心律失常中的作用机制。
Zotero 插件