Sulakvelidze T S
Fiziol Zh SSSR Im I M Sechenova. 1977 Sep;63(9):1326-33.
Antidiuretic and oxytocic activities of venous blood plasma and liquor of ambient cistern of the cerebrum were studied in chronic experiments on alert dogs at different levels of hydration. Liquor was found to have oxytocic activity and practically no antidiuretic activity at ordinary hydration and after two days of thirst. After three days of thirst, dog's liquor caused antidiuretic reaction in rats anesthetized with alcohol, the reaction being lesser than those caused by simultaneously received plasma samples. Liquor displayed an obvious antidiuretic reaction similar to that of vasopressin after prolonged i.v. administration of hypotonic NaCl solution, while plasma samples only had the diuretic effect.
在对清醒犬进行的不同水平水合状态的慢性实验中，研究了大脑环池静脉血浆和脑脊液的抗利尿及催产素活性。发现在正常水合状态及口渴两天后，脑脊液具有催产素活性且几乎没有抗利尿活性。在口渴三天后，犬的脑脊液在酒精麻醉的大鼠中引起抗利尿反应，该反应小于同时采集的血浆样本所引起的反应。在静脉长时间输注低渗氯化钠溶液后，脑脊液显示出与血管加压素相似的明显抗利尿反应，而血浆样本仅有利尿作用。
