Malacinski G M, Bessho T, Yokota C, Fukui A, Asashima M
Department of Biology, Indiana University, Bloomington 47405, USA.
Cell Mol Life Sci. 1997 Apr;53(4):410-7. doi: 10.1007/pl00000614.
As a first step towards providing a conceptual approach to understanding similarities and differences in the mechanisms which guide inductive interactions among related organisms (e.g. various amphibia), a set of five principles is offered here. These principles were formulated by analyzing literature examples of classical embryological phenomena and by performing experiments with activin, a peptide growth factor which is currently suspected to play for a role in mesoderm induction. Mechanisms which account, at least in part, for the observed differences between anuran and urodele inductive processes can be derived from these principles.
作为朝着提供一种概念性方法以理解指导相关生物体(如各种两栖动物)之间诱导性相互作用的机制的异同迈出的第一步,这里提出了一组五条原则。这些原则是通过分析经典胚胎学现象的文献实例以及用激活素进行实验而制定的,激活素是一种肽生长因子,目前被怀疑在中胚层诱导中起作用。至少部分地解释无尾目和有尾目诱导过程之间观察到的差异的机制可以从这些原则中推导出来。