Glasinovic J C, Scrivanti M, Mege R M, Raddatz O, Alvarado A, Valdivia M T, Ahumada E
Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Med Chil. 1996 Jul;124(7):793-8.
There are no chilean reports on gallstone dissolution using oral medications.
To measure the proportion of asymptomatic adult women eligible for gallstone dissolution therapy and to test the effectiveness and tolerance of lovastatin for this purpose.
Three hundred fifty six women working at health care institutions were subjected to a gallbladder ultrasound examination. Non pregnant women with radiolucent gallstones of less than 2 cm phi were invited to receive lovastatin 20 mg od and were followed during six months.
Twenty two women had gallstones and eight eligible women received lovastatin therapy. No reduction in stone size was observed in these women.
Less than half of asymptomatic women with gallstones are eligible for oral dissolution therapy. Lovastatin did not reduce gallstone size after six months of therapy.
智利尚无关于使用口服药物溶解胆结石的报道。
测定符合胆结石溶解疗法的无症状成年女性比例，并为此测试洛伐他汀的有效性和耐受性。
对356名在医疗机构工作的女性进行胆囊超声检查。邀请非妊娠、胆结石直径小于2厘米且透X线的女性服用洛伐他汀，每日20毫克，并随访6个月。
22名女性患有胆结石，8名符合条件的女性接受了洛伐他汀治疗。这些女性的结石大小未观察到减小。
不到一半的无症状胆结石女性符合口服溶解疗法的条件。洛伐他汀治疗6个月后未减小胆结石大小。
