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New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities.

作者信息

Balkan A, Tozkoparan B, Ertan M, Sara Y, Ertekin N

机构信息

Hacettepe University, Faculty of Pharmacy, Dept. of Pharmaceutical Chemistry, Ankara, Turkey.

出版信息

Boll Chim Farm. 1996 Dec;135(11):648-52.

PMID:9138461
Abstract

The synthesis of a series of thiazolo[3,2-a]pyrimidine derivatives were described. The structures of the compounds were elucidated by IR, 1H-NMR, 13C and elementary analysis. The compounds were evaluated for their calcium antagonistic activities using nifedipine as standard compound. All of the compounds were found to be less potent than nifedipine.

摘要

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