Godeau P, Chapelon-Abric C
Service de Médecine Interne-Hôpital de La Pitié, Paris.
Bull Acad Natl Med. 1996 Nov;180(8):2005-15; discussion 2015-8.
This study illustrated 10 cases of sarcoidosis symptomatic cardiomyopathy. All sarcoidosis were confirmed by histology. One was revealed by cardiological signs. Extra-cardiologic manifestations were non specific, as well cardiological and electrical signs. ECG were abnormal in only 70% of cases. Echocardiography and thallium scintigraphy with dipyramidole test were always abnormal. No sudden death appeared in our series. As opposed to all cases in literature, all patients, but one, responded positively to corticotherapy. These results can be explained by high doses of prednisolone associated, when non effective, to another immunosuppressive agent.
本研究阐述了10例结节病症状性心肌病。所有结节病均经组织学确诊。1例由心脏体征发现。心脏外表现无特异性，心脏和电生理体征也无特异性。仅70%的病例心电图异常。超声心动图和双嘧达莫试验铊闪烁显像总是异常。本系列中未出现猝死。与文献中的所有病例相反，除1例患者外，所有患者对皮质激素疗法反应良好。这些结果可以用高剂量泼尼松龙来解释，当无效时，联合使用另一种免疫抑制剂。
