Drannik G N, Man'ko V M, Petrov R V, Sologub P Ia, Sharykina N I
Biull Eksp Biol Med. 1979 Oct;88(10):424-6.
Diiodobenzo-tepa (DIB) was given orally to CBA mice in a dose of 25 mg/kg for 3 successive days. The number of nucleus-containing cells decreased 3.9 fold in the thymus and 1.4 fold in the bone marrow. In experiments on transplantation of lymphoid cells to intact or lethally irradiated (CBA X C57BL/6J)F1 mice treated with DIB this substance did not influence the helper activity of T lymphocytes but inhibited the activity or B and T lymphocytes, inducing "graft-versus-host" and T cell-suppressor functions.
二碘苯替派（DIB）以25毫克/千克的剂量口服给予CBA小鼠，连续3天。含细胞核的细胞数量在胸腺中减少了3.9倍，在骨髓中减少了1.4倍。在用DIB处理的完整或经致死性照射的（CBA×C57BL/6J）F1小鼠进行淋巴细胞移植实验中，该物质不影响T淋巴细胞的辅助活性，但抑制B淋巴细胞和T淋巴细胞的活性，诱导“移植物抗宿主”反应和T细胞抑制功能。
