Pe'er J, Gnessin H, Levinger S, Averbukh E, Levy Y, Polacheck I
Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel.
Arch Pathol Lab Med. 1996 Sep;120(9):854-8.
Conjunctival rhinosporidiosis is an infectious disease rarely recorded outside the Indian subcontinent. The disease is caused by Rhinosporidium seeberi, an endosporulating microorganism of uncertain taxonomic classification. We report a series of cases manifesting this infection.
The demographic, clinical, and histopathologic data of 14 cases of conjunctival rhinosporidiosis on record at our Ophthalmic Pathology Laboratory were reviewed.
All cases were from East Africa; 10 were from Malawi and 4 from Kenya. Ten specimens were from males and three from females. Their age ranged from 7 to 20 years. All patients were treated by surgical excision, and no recurrence was recorded. None of the cases was diagnosed clinically as rhinosporidiosis. Histologically, all stages of the organism's life cycle could be found in the excised tissue, from small trophocytes to large sporangia-containing sporoblasts. There were changes in histochemical stainings with growth and maturation. In general, the inflammation was of chronic nongranulomatous type.
Conjunctival rhinosporidiosis is a rare infectious disease that typically appears in young males in rural regions, and that can be treated by surgical excision. It typically causes chronic nongranulomatous inflammation. Various stages of the R seeberi life cycle can be seen in the affected tissue.
结膜鼻孢子虫病是一种在印度次大陆以外很少有记录的传染病。该疾病由西伯鼻孢子菌引起，西伯鼻孢子菌是一种分类地位不确定的内生孢子微生物。我们报告了一系列表现出这种感染的病例。
回顾了我们眼科病理实验室记录的14例结膜鼻孢子虫病患者的人口统计学、临床和组织病理学数据。
所有病例均来自东非；10例来自马拉维，4例来自肯尼亚。10份标本来自男性，3份来自女性。他们的年龄在7至20岁之间。所有患者均接受手术切除治疗，未记录到复发情况。所有病例在临床上均未被诊断为鼻孢子虫病。在组织学上，从微小滋养细胞到含有大孢子囊的孢子母细胞，在切除的组织中可以发现该生物体生命周期的各个阶段。随着生长和成熟，组织化学染色发生变化。总体而言，炎症为慢性非肉芽肿性炎症。
结膜鼻孢子虫病是一种罕见的传染病，通常出现在农村地区的年轻男性中，可通过手术切除治疗。它通常引起慢性非肉芽肿性炎症。在受影响的组织中可以看到西伯鼻孢子菌生命周期的各个阶段。
