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板层角膜移植物治疗伴有巩膜溶解的结膜鼻孢子虫病。

Tectonic corneal graft for conjunctival rhinosporidiosis with scleral melt.

机构信息

Department of Ophthalmology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

出版信息

Indian J Ophthalmol. 2011 May-Jun;59(3):251-3. doi: 10.4103/0301-4738.81046.

DOI:10.4103/0301-4738.81046
PMID:21586855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3120253/
Abstract

A 16 year old girl presented with irritation and watering of the right eye for 3 months. On examination, the superior perilimbal sclera was ectatic with incarcerated uveal tissue covered by conjunctiva. The conjunctiva showed discreet, yellow white mucoid spots. Excision biopsy of the conjunctiva showed subepithelial spherules of sporangia containing numerous endospores, suggestive of rhinosporidiosis. Diathermy was applied to flatten the staphyloma. The ectatic area was covered with a corneal patch graft. The patient was started on prednisolone acetate eye drops and oral dapsone for 6 months. Corneal graft was well incorporated and conjunctivalized by 3 months. Since the graft was not seen within the palpebral aperture, there was good cosmetic result. The corneal graft had the added advantage of transparency which allowed visualization of the underlying tissue to diagnose early recurrence. There was no recurrence at 6 months.

摘要

一位 16 岁女孩因右眼刺激和流泪 3 个月就诊。检查发现，上险周巩膜扩张，有葡萄膜组织嵌顿，表面覆盖结膜。结膜上有散在的、黄白色黏液样斑点。结膜切除活检显示，上皮下有包含大量内生孢子的孢子囊小体，提示为鼻孢子虫病。对葡萄膜膨出区行透热疗法以使其平复。用角膜贴片覆盖扩张区。患者开始接受醋酸泼尼松龙滴眼液和口服氨苯砜治疗 6 个月。角膜移植片 3 个月时已完全融合和结膜化。由于移植片未在睑裂内看到，因此外观良好。角膜移植片的另一个优点是透明，可观察到下方组织，从而早期发现复发。6 个月时无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/fd627f1fe2c4/IJO-59-251-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/9851a4d8acc0/IJO-59-251-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/2dfa2e7435a9/IJO-59-251-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/8457fc586fe4/IJO-59-251-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/fd627f1fe2c4/IJO-59-251-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/9851a4d8acc0/IJO-59-251-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/2dfa2e7435a9/IJO-59-251-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/8457fc586fe4/IJO-59-251-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b5e/3120253/fd627f1fe2c4/IJO-59-251-g004.jpg

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本文引用的文献

1
Structural and functional outcome of scleral patch graft.巩膜补片移植的结构和功能结果。
Eye (Lond). 2007 Jul;21(7):930-5. doi: 10.1038/sj.eye.6702344. Epub 2006 Apr 7.
2
Conjunctival oculosporidiosis with scleral thinning and staphyloma formation.
Indian J Ophthalmol. 2005 Dec;53(4):272-4. doi: 10.4103/0301-4738.18912.
3
Surgical management of scleral defects.巩膜缺损的手术治疗
Cornea. 2005 Apr;24(3):308-11. doi: 10.1097/01.ico.0000141228.10849.17.
巴西东北部马拉尼昂州一家公立医院确诊的眼部鼻孢子虫病病例评估。
BMC Ophthalmol. 2019 Nov 8;19(1):218. doi: 10.1186/s12886-019-1223-x.
4
Partial regression of large anterior scleral staphyloma secondary to rhinosporidiosis after corneoscleral graft - a case report.角膜巩膜移植术后鼻孢子虫病继发的大型前巩膜葡萄肿部分消退——病例报告
BMC Ophthalmol. 2018 Feb 27;18(1):61. doi: 10.1186/s12886-018-0725-2.
5
Disseminated Rhinosporidiosis with Conjunctival Involvement in an Immunocompromised Patient.免疫功能低下患者并发结膜受累的播散性鼻孢子虫病。
Middle East Afr J Ophthalmol. 2017 Jan-Mar;24(1):51-53. doi: 10.4103/meajo.MEAJO_89_15.
6
Rhinosporidiosis of the tarsal conjunctiva.睑结膜鼻孢子虫病。
Indian J Ophthalmol. 2015 May;63(5):462-3. doi: 10.4103/0301-4738.159897.
7
Ocular rhinosporidiosis mimicking conjunctival squamous papilloma in Kenya - a case report.肯尼亚眼部罗氏孢子虫病酷似结膜鳞状上皮乳头状瘤——一例报告。
BMC Ophthalmol. 2014 Apr 8;14:45. doi: 10.1186/1471-2415-14-45.
4
OCULOSPORIDIOSIS: RHINOSPORIDIOSIS OF THE EYE.眼孢子丝菌病：眼部鼻孢子菌病
Br J Ophthalmol. 1963 Jun;47(6):346-9. doi: 10.1136/bjo.47.6.346.
5
Amniotic membrane graft for the management of scleral melting and corneal perforation in recalcitrant infectious scleral and corneoscleral ulcers.羊膜移植治疗难治性感染性巩膜及角膜巩膜溃疡的巩膜溶解和角膜穿孔
Cornea. 2002 Apr;21(3):275-83. doi: 10.1097/00003226-200204000-00008.
6
Oculosporidiosis in Northern India.
Indian Pediatr. 2001 May;38(5):540-3.
7
Multilayered amniotic membrane transplantation for severe ulceration of the cornea and sclera.多层羊膜移植治疗角膜和巩膜严重溃疡
Am J Ophthalmol. 2001 Mar;131(3):324-31. doi: 10.1016/s0002-9394(00)00825-4.
8
Conjunctival rhinosporidiosis associated with scleral melting and staphyloma formation: diagnosis and management.伴有巩膜溶解和葡萄肿形成的结膜鼻孢子虫病：诊断与处理
Cornea. 2000 Jan;19(1):30-3. doi: 10.1097/00003226-200001000-00007.
9
Phylogenetic analysis of Rhinosporidium seeberi's 18S small-subunit ribosomal DNA groups this pathogen among members of the protoctistan Mesomycetozoa clade.对西伯鼻孢子菌18S小亚基核糖体DNA的系统发育分析将这种病原体归类于原生动物中黏菌虫纲的成员之中。
J Clin Microbiol. 1999 Sep;37(9):2750-4. doi: 10.1128/JCM.37.9.2750-2754.1999.
10
Prevalence of rhinosporidiosis of the eye and its adnexa in Nepal.尼泊尔眼部及其附属器鼻孢子虫病的患病率。
Am J Trop Med Hyg. 1998 Aug;59(2):231-4. doi: 10.4269/ajtmh.1998.59.231.