de Groot C M, Yeates K O, Baker G B, Bornstein R A
Tourette Laboratory, Ohio State University, Columbus 43210, USA.
J Neuropsychiatry Clin Neurosci. 1997 Spring;9(2):267-72. doi: 10.1176/jnp.9.2.267.
This study examined neuropsychological performance by 92 children with Tourette's syndrome (TS) grouped by the presence or absence of obsessive-compulsive and/or attention deficit symptoms. The identified groups did not differ with respect to age, education, age at onset of TS symptoms, or medication use. After statistical control for complex motor symptoms, impaired performance on measures of achievement and executive functioning was correlated with obsessive and obsessive/attention symptoms, but not with attention symptoms alone. The presence of both obsessive and attention symptoms identified children with impairment across several tasks. Clinical and functional implications are discussed.
本研究对92名患有妥瑞氏综合征（TS）的儿童的神经心理表现进行了检查，这些儿童根据是否存在强迫和/或注意力缺陷症状进行分组。所确定的组在年龄、教育程度、TS症状发作年龄或用药情况方面没有差异。在对复杂运动症状进行统计控制后，学业成绩和执行功能测量方面的表现受损与强迫及强迫/注意力症状相关，但与单独的注意力症状无关。强迫和注意力症状同时存在表明儿童在多项任务中存在损伤。文中讨论了其临床和功能意义。
