Tappe U, Kristen F, Löffler A, Keller H W
Innere Abteilung, Malteserkrankenhauses Bonn.
Dtsch Med Wochenschr. 1997 Apr 11;122(15):471-4. doi: 10.1055/s-2008-1047640.
A 58-year-old man was hospitalized because of acute dull upper abdominal pain, radiating into the right flank and lower abdomen. The past history was unremarkable expect for thyroidectomy, performed 30 years previously for thyroid carcinoma. There was painful resistance on palpation of the right upper abdomen. The patient had not recently sustained any trauma. BIOCHEMICAL AND IMAGING INVESTIGATIONS: Erythrocyte sedimentation rate was increased to 38 mm/h, haemoglobin concentration was 11.7 g/dl but fell to 9.9 g/dl within the first 24 hours. Ultrasound and computed tomography (CT) revealed a large retroperitoneal mass (5 x 6.5 x 15 cm), its density of 64 Hounsfield units most strongly suggesting an haematoma. CT also showed enlargement of the right adrenal. Chest radiography demonstrated a space-occupying lesion in the right upper lobe.
DIAGNOSIS, TREATMENT AND COURSE: As a retroperitoneal haematoma of uncertain aetiology was suspected, a laparotomy was performed. The haematoma was evacuated and the adrenal, showing tumours changes, was excised. Histologically it was a mucocellular metastasis. The chest radiograph suggested carcinoma of the lung as the primary. The illness took a rapidly fatal course. Autopsy confirmed a poorly differentiated adenocarcinoma of the lung.
Trauma or anticoagulation should be considered first in the differential diagnosis of retroperitoneal haematoma of uncertain aetiology. However, adrenal metastasis should be thought of as a rare possibility.
一名58岁男性因上腹部钝痛并向右腰及下腹部放射而入院。既往史无特殊,30年前因甲状腺癌行甲状腺切除术。右上腹触诊有压痛性抵抗。患者近期无外伤史。
红细胞沉降率增至38mm/h,血红蛋白浓度为11.7g/dl,但在最初24小时内降至9.9g/dl。超声及计算机断层扫描(CT)显示腹膜后有一巨大肿块(5×6.5×15cm),其密度为64亨氏单位,高度提示为血肿。CT还显示右侧肾上腺增大。胸部X线片显示右上叶有占位性病变。
诊断、治疗及病程:由于怀疑为病因不明的腹膜后血肿,遂行剖腹探查术。清除血肿并切除有肿瘤改变的肾上腺。组织学检查为黏液细胞转移瘤。胸部X线片提示原发性肺癌。病情发展迅速,最终死亡。尸检证实为低分化肺腺癌。
在鉴别病因不明的腹膜后血肿时,首先应考虑外伤或抗凝因素。然而,肾上腺转移瘤应视为一种罕见的可能性。