Panhuyzen-Goedkoop N M, Crijns H J
Diakonessenhuis, afd. Cardiologie, Utrecht.
Ned Tijdschr Geneeskd. 1997 Feb 8;141(6):273-7.
In four patients, two men aged 65 and 35 years, and two women aged 87 and 83 years, who presented with collapse, administration of Q-T time prolonging drugs (sotalol, erythromycin, disopyramide) appeared to be the cause. These patients had so-called 'concealed long Q-T syndrome'. The proarrhythmogenic properties of antiarrhythmic and other drugs and of several clinical conditions such as cardiac diseases should be kept in mind when treating patients with antiarrhythmic substances.
在4例患者中,2名男性,年龄分别为65岁和35岁,2名女性,年龄分别为87岁和83岁,他们均因虚脱就诊,使用延长Q-T间期的药物(索他洛尔、红霉素、丙吡胺)似乎是病因。这些患者患有所谓的“隐匿性长Q-T综合征”。在使用抗心律失常药物治疗患者时,应牢记抗心律失常药物及其他药物以及某些临床情况(如心脏病)的促心律失常特性。