气相色谱法测定生物样品中芬氟拉明和去甲芬氟拉明的光学异构体 - Suppr

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Gas-liquid chromatographic determination of the optical isomers of fenfluramine and norfenfluramine in biological samples.

作者信息

Caccia S, Jori A

出版信息

J Chromatogr. 1977 Nov 21;144(1):127-31. doi: 10.1016/0021-9673(77)80016-2.

DOI:10.1016/0021-9673(77)80016-2

PMID:914957

Abstract

摘要

相似文献

Gas-liquid chromatographic determination of the optical isomers of fenfluramine and norfenfluramine in biological samples.气相色谱法测定生物样品中芬氟拉明和去甲芬氟拉明的光学异构体

J Chromatogr. 1977 Nov 21;144(1):127-31. doi: 10.1016/0021-9673(77)80016-2.

Improved gas-liquid chromatographic method for measuring fenfluramine and norfenfluramine in heparinised plasma.用于测定肝素化血浆中芬氟拉明和去甲芬氟拉明的改良气液色谱法。

J Chromatogr. 1983 Dec 9;278(2):434-8. doi: 10.1016/s0378-4347(00)84805-7.

Enantioselective gas chromatographic assay with electron-capture detection for dl-fenfluramine and dl-norfenfluramine in plasma.血浆中右芬氟拉明和去甲右芬氟拉明的对映体选择性气相色谱-电子捕获检测法测定

J Chromatogr. 1988 Dec 9;433:105-17. doi: 10.1016/s0378-4347(00)80589-7.

Determination of fenfluramine and norfenfluramine in plasma using a nitrogen-sensitive detector.使用氮敏感检测器测定血浆中芬氟拉明和去甲芬氟拉明。

J Chromatogr. 1984 Oct 12;310(2):412-7. doi: 10.1016/0378-4347(84)80109-7.

The measurement of d-fenfluramine and its metabolite, d-norfenfluramine in plasma and urine with an application of the method to pharmacokinetic studies.

Xenobiotica. 1989 May;19(5):547-53. doi: 10.3109/00498258909042294.

Proceedings: The relationship between fenfluramine and norfenfluramine blood levels and anoretic activity in the rat.论文集：大鼠中芬氟拉明和去甲芬氟拉明血药浓度与厌食活性之间的关系。

Br J Pharmacol. 1975 Oct;55(2):261P.

Pharmacokinetics of fenfluramine and norfenfluramine in volunteers given D- and DL-fenfluramine for 15 days.给予D-和DL-芬氟拉明15天的志愿者体内芬氟拉明和去甲芬氟拉明的药代动力学

Eur J Clin Pharmacol. 1985;29(2):221-4. doi: 10.1007/BF00547426.

Fluorometric determination of DL-fenfluramine, DL-norfenfluramine and phentermine in plasma by achiral and chiral high-performance liquid chromatography.通过非手性和手性高效液相色谱法荧光测定血浆中的右旋芬氟拉明、去甲右旋芬氟拉明和苯丁胺。

J Chromatogr B Biomed Sci Appl. 2001 Nov 5;763(1-2):79-90. doi: 10.1016/s0378-4347(01)00368-1.

Metabolism of fenfluramine to norfenfluramine in guinea-pigs.芬氟拉明在豚鼠体内代谢为去甲芬氟拉明。

J Pharm Pharmacol. 1988 Jun;40(6):439-41. doi: 10.1111/j.2042-7158.1988.tb06312.x.

Interactions of iprindole with fenfluramine metabolism in rat brain and liver.异吲哚酮与芬氟拉明在大鼠脑和肝脏中的代谢相互作用。

J Psychiatry Neurosci. 1991 Mar;16(1):5-11.

引用本文的文献

Kinetics of fenfluramine isomers in the rat.芬氟拉明异构体在大鼠体内的动力学

Eur J Drug Metab Pharmacokinet. 1981;6(4):297-301. doi: 10.1007/BF03189529.

Eur J Clin Pharmacol. 1985;29(2):221-4. doi: 10.1007/BF00547426.

Anorectic effect of fenfluramine isomers and metabolites: relationship between brain levels and in vitro potencies on serotonergic mechanisms.芬氟拉明异构体和代谢物的厌食作用：脑内水平与对血清素能机制的体外效力之间的关系。

Psychopharmacology (Berl). 1985;85(1):111-4. doi: 10.1007/BF00427333.

Pharmacokinetics of fenfluramine enantiomers in man.

Eur J Drug Metab Pharmacokinet. 1979;4(3):129-32. doi: 10.1007/BF03189414.

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