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高压性反射亢进:43个大气压下人体的腱反射和霍夫曼反射

Hyperbaric hyperreflexia: tendon-jerk and Hoffmann reflexes in man at 43 bars.

作者信息

Harris D J

出版信息

Electroencephalogr Clin Neurophysiol. 1979 Dec;47(6):680-92. doi: 10.1016/0013-4694(79)90295-5.

DOI:10.1016/0013-4694(79)90295-5
PMID:91497
Abstract

Tendon jerk (TJR) and Hoffmann (H) reflexes of the soleus muscle were studied in two men during a 26-day simulated oxygenhelium dive to a maximum pressure of 43 bars. The amplitude of the TJR response was observed to increase markedly after compression and also at the end of decompression. This biphasic pattern of enhanced reflectivity was reproduced by synchronised but much smaller variations in H reflex response. The positive facilitatory effects of applying Jenkdrassik's manoeuvre were reduced and the negative effects increased during hyperbaric exposure. Excitability cycles (twin-pulses methods) revealed modifications in one subject similar to those observed in clinical hyperreflexia, namely a shortening of Phase III and an enhancement of Phase IV. The other subject exhibited a notable depression of Phase IV. Abnormal EMG recordings are described including randomly-triggered slow wave potentials with no mechanical effects, and fixed, long latency late responses of a reflex nature with a definite mechanical effect. The contention that alterations in vestibulo-spinal relations may result in the release from tonic presynaptic inhibitory control of myotatic reflex arc excitability is discussed as a partial explanation for these and related findings.

摘要

在为期26天的模拟氧氦潜水至最大压力43巴的过程中,对两名男性的比目鱼肌腱反射(TJR)和霍夫曼(H)反射进行了研究。观察到TJR反应的幅度在加压后以及减压结束时均显著增加。通过H反射反应中同步但小得多的变化,重现了这种反射增强的双相模式。在高压暴露期间,应用詹德拉斯基动作的正促进作用减弱,负作用增强。兴奋性周期(双脉冲方法)显示,一名受试者出现了与临床反射亢进中观察到的类似变化,即III期缩短和IV期增强。另一名受试者IV期则显著降低。描述了异常的肌电图记录,包括无机械效应的随机触发慢波电位,以及具有明确机械效应的固定、长潜伏期反射性晚期反应。作为对这些及相关发现的部分解释,讨论了前庭-脊髓关系的改变可能导致牵张反射弧兴奋性的紧张性突触前抑制控制解除这一观点。

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