Takamura K, Nasuhara Y, Mishina T, Matsuda T, Nishimura M, Kawakami Y, Fujita M, Mikuni C, Yamashiro K
First Department of Medicine, Hokkaido University, Sapporo, Japan.
Eur Respir J. 1997 Apr;10(4):955-7.
Intravascular lymphomatosis is a rare lymphoma presenting a variety of symptoms due to proliferation of tumour cells within blood vessels in the brain, the skin and other organs. This disease is generally considered to be highly malignant, but to be relatively susceptible to combined chemotherapy, when diagnosed in the early stage. We describe a case of intravascular lymphomatosis, presenting with diffuse interstitial shadows on chest radiographic image, which could be diagnosed by transbronchial lung biopsy. The patient showed a good response to combined chemotherapy. We propose that transbronchial lung biopsy is a useful procedure for the diagnosis of intravascular lymphomatosis.
血管内淋巴瘤是一种罕见的淋巴瘤,由于肿瘤细胞在脑、皮肤和其他器官的血管内增殖而呈现出多种症状。这种疾病通常被认为具有高度恶性,但在早期诊断时相对容易对联合化疗敏感。我们描述了一例血管内淋巴瘤病例,胸部X线影像显示弥漫性间质阴影,通过经支气管肺活检得以确诊。该患者对联合化疗反应良好。我们认为经支气管肺活检是诊断血管内淋巴瘤的一种有用方法。