Reider C R, Paulson G W
Department of Neurology, Ohio State University, Columbus, USA.
Arch Neurol. 1997 May;54(5):527-8. doi: 10.1001/archneur.1997.00550170013008.
Investigators are beginning to reexamine the use of vitamin E for the treatment of amyotrophic lateral sclerosis. Vitamin E was isolated in the 1920s, and the results of animal studies led rapidly to clinical use. Regrettably, vitamin E did not ameliorate the progression of amyotrophic lateral sclerosis for Lou Gehrig, but more recent advances may identify subpopulations that do respond to vitamin E.
研究人员开始重新审视维生素E在治疗肌萎缩侧索硬化症方面的应用。维生素E于20世纪20年代被分离出来,动物研究结果迅速推动了其临床应用。遗憾的是,维生素E并未能改善卢·格里克所患的肌萎缩侧索硬化症的病情发展,但最近的进展可能会确定对维生素E有反应的亚人群。