Straznicky K, Tay D
J Embryol Exp Morphol. 1977 Aug;40:175-85.
The growth of normal and surgically produced compound dorsal and ventral retinae in Xenopus laevis has been studied autoradiographically following injections of [3H] thymidine at stages 50 and 58. The animals were sacrificed 3 weeks after metamorphosis. The histogenetic pattern of the dorsal and ventral retinal halves was different at the three time points investigated, i.e. up to stage 50, between stages 50 and 58 and between stage 58 and 3 weeks after metamorphosis. Asymmetrical dorsal retinal growth occurred up to stage 50. From stage 50 onwards the retinal growth tendency reversed so that more ganglion cells were produced along the ventral than the dorsal ciliary margins. The overall preponderance of ventral retinal growth was 32.4% in cell number and 12.4% in retinal length from early embryogenesis to 3 weeks after metamorphosis. The characteristic histogenetic pattern of the dorsal and ventral retinal halves was maintained in an ectopic position in the compound eye, indicating that this particular property of the retinal halves is intrinsically determined.
在非洲爪蟾发育的第50阶段和第58阶段注射[3H]胸腺嘧啶核苷后，利用放射自显影技术研究了正常及手术产生的复合背侧和腹侧视网膜的生长情况。动物在变态发育3周后被处死。在所研究的三个时间点，即发育至第50阶段前、第50阶段至第58阶段之间以及第58阶段至变态发育后3周之间，背侧和腹侧视网膜半区的组织发生模式有所不同。在第50阶段之前，背侧视网膜出现不对称生长。从第50阶段起，视网膜生长趋势逆转，使得沿腹侧睫状缘产生的神经节细胞比背侧更多。从胚胎早期发育到变态发育后3周，腹侧视网膜生长在细胞数量上总体占优势32.4%，在视网膜长度上占优势12.4%。背侧和腹侧视网膜半区的特征性组织发生模式在复眼中的异位位置得以维持，这表明视网膜半区的这种特殊性质是由内在因素决定的。
