Nakamura K, Shimai S, Kikuchi S, Tominaga K, Takahashi H, Tanaka M, Nakano S, Motohashi Y, Nakadaira H, Yamamoto M
Department of Hygiene and Preventive Medicine, Niigata University, School of Medicine, Japan.
Occup Med (Lond). 1997 Apr;47(3):142-6. doi: 10.1093/occmed/47.3.142.
This study was conducted to determine if there is an association between shift work and risk factors for coronary heart disease (CHD) in Japanese male blue-collar shift workers. Health check-up data on serum lipid concentration and anthropometric indices of 33 three-shift workers and 27 two-shift workers were compared with those of day workers. The average years in age of the shift workers and day workers were 34.5 (SD = 7.1) and 32.7 (SD = 7.6), respectively. Serum total cholesterol levels of three-shift, two-shift and day workers were 5.70 (SD = 1.19) mmol/l, 4.81 (SD = 1.01) mmol/l, 4.98 (SD = 0.95) mmol/l, respectively, and the cholesterol levels of three-shift workers were significantly higher than the other workers (p < 0.05). In addition, the abdominal to hip circumference ratios were 0.905 (SD = 0.060) for three-shift workers and 0.877 (SD = 0.054) for day workers, with a significant difference (p < 0.05). In the present Japanese population, three-shift workers had higher risks of CHD than day workers, which was characterized by higher levels of serum total cholesterol and tendency to central obesity. These findings held when lifestyle factors were taken into account.
本研究旨在确定日本男性蓝领轮班工人的轮班工作与冠心病（CHD）危险因素之间是否存在关联。将33名三班制工人和27名两班制工人的血脂浓度和人体测量指标的健康检查数据与日班工人的数据进行比较。轮班工人和日班工人的平均年龄分别为34.5岁（标准差=7.1）和32.7岁（标准差=7.6）。三班制、两班制和日班工人的血清总胆固醇水平分别为5.70（标准差=1.19）mmol/l、4.81（标准差=1.01）mmol/l、4.98（标准差=0.95）mmol/l，三班制工人的胆固醇水平显著高于其他工人（p<0.05）。此外，三班制工人的腹臀围比为0.905（标准差=0.060），日班工人为0.877（标准差=0.054），差异显著（p<0.05）。在目前的日本人群中，三班制工人患冠心病的风险高于日班工人，其特征是血清总胆固醇水平较高和有向心性肥胖的倾向。考虑生活方式因素时，这些发现依然成立。
