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[去神经支配后青蛙神经肌肉突触终末的超微结构]

[The ultrastructure of the neuromuscular synaptic terminal in the frog after denervation].

作者信息

Bezgina E N, Kashapova L A

出版信息

Morfologiia. 1997;111(1):53-7.

PMID:9156754
Abstract

Ultrastructure of certain myoneural terminals were studied on serial sections on day 3, 5 and 8 after denervation. Ultrastructure of the terminal proximal and distal regions and Schwann cell were studied by means of morphometry and reconstruction of single terminals. On day 3 after denervation Schwann cell is activated in terminal proximal regions more rapidly than in distal ones with contractility in the terminal proximal region being more significant than in distal. On day 5 after denervation changes cover both initial and terminal regions and on day 8 almost all the regions where terminal were placed earlier were occupied with Schwann cell. A suggestion is made that structural changes in the Schwann cell-terminal system are the major contributors to decrease of synaptic discharge in early stages of denervation and appearance of Schwann cell potentials in more late ones.

摘要

在去神经支配后的第3天、第5天和第8天,对某些肌神经终末的超微结构进行了连续切片研究。通过形态计量学和单个终末的重建,研究了终末近端和远端区域以及施万细胞的超微结构。去神经支配后第3天,施万细胞在终末近端区域比远端区域更迅速地被激活,终末近端区域的收缩性比远端更显著。去神经支配后第5天,变化覆盖起始和终末区域,到第8天,几乎所有先前终末所在的区域都被施万细胞占据。有人提出,施万细胞 - 终末系统的结构变化是去神经支配早期突触放电减少以及后期施万细胞电位出现的主要原因。

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