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[手术性脓毒症的多模式治疗]

[The multimodal therapy of surgical sepsis].

作者信息

Briusov P G, Kostiuchenko A L

出版信息

Voen Med Zh. 1997 Mar;318(3):28-34, 80.

PMID:9157692
Abstract

The data of clinical current of sepsis in 239 wounded with syndrome of system inflammatory reaction (SIR) are investigated. Frequency of sepsis in complications of gun-shot wounds has made 5.4%. At the same time syndrome SIR is diagnosed in 23.4% of cases, that was the indication to realization of the whole complex of antiseptic treatment. Therapy of sepsis included some components: drainage and removal of the septic center; the system antibacterial therapy; the controlled hypocoagulation; immunotherapy; active detoxication; power and trophic support on the basis of balanced feed. The used principles of early diagnostics and multicomponent therapy of surgery of sepsis have allowed to lower lethality up to 29.3% and in sepsis of wound--up to 9.1%.

摘要

对239例伴有全身炎症反应综合征(SIR)的伤员的脓毒症临床数据进行了研究。枪伤并发症中脓毒症的发生率为5.4%。同时,23.4%的病例诊断为SIR综合征,这是实施整套抗菌治疗的指征。脓毒症的治疗包括几个方面:引流和清除感染源;系统抗菌治疗;控制性低凝;免疫治疗;积极解毒;基于均衡喂养的能量和营养支持。所采用的脓毒症手术早期诊断和多组分治疗原则已使死亡率降至29.3%,伤口脓毒症死亡率降至9.1%。

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