Kimura I, Yamamoto S, Yamura T
Int Arch Allergy Appl Immunol. 1979;60(4):465-8. doi: 10.1159/000232378.
An in vitro release of the eosinophil chemotactic factor of anaphylaxis (ECF-A) in anaphylactic reactions was studied using skin slices from actively sensitized guinea pigs. ECF-A and histamine were released in vitro from actively sensitized guinea pig skin by antigen challenge. The magnitude of ECF-A release did not always parallel that of anaphylactic histamine release in guinea pig skin, suggesting that there may be no correlation between the amount of ECF-A and that of histamine released from the skin in anaphylactic reactions in guinea pigs.
利用主动致敏豚鼠的皮肤切片，研究了过敏反应中过敏嗜酸性粒细胞趋化因子（ECF-A）的体外释放情况。通过抗原激发，在体外从主动致敏的豚鼠皮肤中释放出ECF-A和组胺。豚鼠皮肤中ECF-A释放的程度并不总是与过敏组胺释放的程度平行，这表明在豚鼠过敏反应中，从皮肤释放的ECF-A量与组胺量之间可能不存在相关性。
