蛋白质和RNA的核输出
Nuclear export of proteins and RNAs.
作者信息
Nakielny S, Dreyfuss G
机构信息
Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6148, USA.
出版信息
Curr Opin Cell Biol. 1997 Jun;9(3):420-9. doi: 10.1016/s0955-0674(97)80016-6.
PMID:9159083
Abstract
Our understanding of protein export from the nucleus to the cytoplasm has been advanced recently by the discovery of active, signal-mediated export pathways. Nuclear export signals have been identified in several proteins, the majority of which are RNA-binding proteins. Nuclear export of RNA molecules is likely to be driven by protein-based nuclear export signals.
摘要
最近，通过发现活跃的、信号介导的输出途径，我们对蛋白质从细胞核输出到细胞质的理解取得了进展。在几种蛋白质中已鉴定出核输出信号，其中大多数是RNA结合蛋白。RNA分子的核输出可能由基于蛋白质的核输出信号驱动。
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