Ford C W, Hamel J C, Stapert D, Moerman J K, Hutchinson D K, Barbachyn M R, Zurenko G E
Pharmacia & Upjohn Inc., Kalamazoo, MI 49001, USA.
Trends Microbiol. 1997 May;5(5):196-200. doi: 10.1016/S0966-842X(97)01032-9.
The oxazolidinones are a new chemical class of synthetic antibacterial agents that are active orally or intravenously against multidrug-resistant Gram-positive bacteria. Their unique mechanism of action and activity against bacteria that pose therapeutic problems in hospital and community treatments make them promising candidates for antimicrobial agents.
恶唑烷酮类是一类新型的合成抗菌剂,口服或静脉给药时对多重耐药革兰氏阳性菌具有活性。它们独特的作用机制以及对在医院和社区治疗中造成治疗难题的细菌的活性,使其成为很有前景的抗菌剂候选药物。