Gruber A J, Pope H G, Brown M E
Biological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts 02178, USA.
Depression. 1996;4(2):77-80. doi: 10.1002/(SICI)1522-7162(1996)4:2<77::AID-DEPR7>3.0.CO;2-C.
Several lines of evidence suggest that cannabis may have antidepressant effects. However, methodologic limitations in available studies make the results difficult to interpret. We review this literature and present five cases in which the evidence seems particularly clear that marijuana produced a direct antidepressant effect. If true, these observations argue that many patients may use marijuana to "self-treat" depressive symptoms.
多项证据表明大麻可能具有抗抑郁作用。然而，现有研究中的方法学局限性使得结果难以解释。我们回顾了这一文献，并列举了五个案例，其中大麻产生直接抗抑郁作用的证据似乎特别明显。如果属实，这些观察结果表明许多患者可能会使用大麻来“自我治疗”抑郁症状。
