Krishna P D, Newhouse V L
Biomedical Engineering and Science Institute, Drexel University, Philadelphia, PA 19104, USA.
Ultrasound Med Biol. 1997;23(3):453-9. doi: 10.1016/s0301-5629(96)00217-7.
Techniques necessary for measurement of the second harmonic of the insonifying frequency backscattered from ultrasonic contrast agents are described, and used to determine this characteristic for the agents Albunex and FSO69. The results confirm theoretical predictions that scattered second harmonic pressure is proportional to the square of the incident pressure. Because contrast agents of the type investigated improve discrimination of blood echoes against tissue echoes by means of the second harmonic of the insonifying frequency, these results allow a comparison of the relative merits of Albunex and FSO69 for harmonic imaging.
本文描述了测量从超声造影剂反向散射的声频二次谐波所需的技术，并将其用于测定Albunex和FSO69这两种造影剂的该特性。结果证实了理论预测，即散射二次谐波压力与入射压力的平方成正比。由于所研究类型的造影剂通过声频二次谐波提高了血液回波相对于组织回波的辨别能力，这些结果使得能够比较Albunex和FSO69在谐波成像方面的相对优点。
