Altwein J E, Jonas U, Hohenfellner R
J Urol. 1977 Nov;118(5):832-6. doi: 10.1016/s0022-5347(17)58211-7.
Sixty-four children underwent colon conduit urinary diversion because of a neurogenic bladder owing to myelomeningocele and 39 children required a ureterosigmoidostomy because of bladder exstrophy. The average length of followup was 4.6 years after colon conduit and 5.6 years after ureterosigmoidostomy. Colon conduit diversion was secondary in 3 children and ureterosigmoidostomy was secondary in 5. Of the children with a colon conduit 9.4% and of those with ureterosigmoidostomy 12.8% had postoperative surgical complications. Late surgical complications were encountered after colon conduit in 14.5% and after ureterosigmoidostomy in 20%. Of the children with normal renal function preoperatively 8.3% showed late deterioration after colon conduit and 8.7% after ureterosigmoidostomy. Conversely, only 16.7% with impaired renal function preoperatively did not improve at long-term followup after colon conduit. Of the renoureteral units 91% were normal after colon conduit and 95.2% were normal after ureterosigmoidostomy. The colon conduit halted the preoperative pyelonephritis in 74% of 31 affected kidneys.
64名儿童因脊髓脊膜膨出导致神经源性膀胱而接受了结肠代膀胱尿流改道术,39名儿童因膀胱外翻而需要行输尿管乙状结肠吻合术。结肠代膀胱术后的平均随访时间为4.6年,输尿管乙状结肠吻合术后为5.6年。3名儿童的结肠代膀胱术为二期手术,5名儿童的输尿管乙状结肠吻合术为二期手术。接受结肠代膀胱术的儿童中有9.4%、接受输尿管乙状结肠吻合术的儿童中有12.8%发生了术后手术并发症。结肠代膀胱术后14.5%出现晚期手术并发症,输尿管乙状结肠吻合术后20%出现晚期手术并发症。术前肾功能正常的儿童中,结肠代膀胱术后8.3%出现晚期肾功能恶化,输尿管乙状结肠吻合术后8.7%出现晚期肾功能恶化。相反,术前肾功能受损的儿童中,结肠代膀胱术后长期随访时只有16.7%没有改善。结肠代膀胱术后91%的肾输尿管单位正常,输尿管乙状结肠吻合术后95.2%的肾输尿管单位正常。结肠代膀胱术使31个受影响肾脏中的74%的术前肾盂肾炎得到缓解。